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Nanofabricated chips are nanoscale semiconductors that can be used as implantable microchips that automatically control the release of a drug from a pump or other source into the body as needed. Microelectromechanical systems (MEMS) combine computers with tiny mechanical devices such as sensors, valves, gears, mirrors, and actua tors that are embedded in semiconductor chips. MEMS are being used to develop miniature, implantable drug pumps and sensors that function as self-contained drug delivery and monitoring systems. Similarly, molecular manufacturing and nanobots have application ranging from rapid develop ment of designer drugs to programmable, miniature robots that can deliver drugs directly to diseased cells.

Figure 1.2.1 The snow density profile measured by H. Rott at Vestestraumen. The profile was obtained by measuring the average density in consecutive 5-cm layers.

layer density variations are assumed to be normally distributed and are then superimposed on top of the background exponential profile. The profile is carried down to 10-m depth. Below this depth, layered scattering is expected to drop off. The temperature profile is again assumed to have the form of To+Th exp(,z). Since the measurements were made in the Antarctic summer, the temperature distribution decays from a high temperature at the surface down to the mean annual temperature at depths greater than 10 m. Figure 1.2.2 shows two sample theoretical profiles generated. The layer thickness is exponentially distributed with a mean layer thickness of 4.1 em. The density

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After creating the MDI parent form, create all the forms that appear within it These MDI child forms provide the user interface for all the features of your application You create an MDI child form just like you create any other form The form becomes an MDI child form by setting its MdiParent property at runtime To add an MDI child form to your application: 1 Create a form Any form can be an MDI child form

p(z) = 0.25 + 0.16 [1 - exp(0.05z)]

+ Pf(z)

(1.2.1)

with z in centimeters. The fluctuating part Pf (z) is normally distributed with standard deviation of of 0.04 gjcma. Both parameters of layer thickness and density fluctuation are very different from that of the continuous random medium model. The continuous random medium model used lz = 2 m and density fluctuation of 0.0156 gjcm a. Figure 1.2.3 shows the corresponding histogram of the densities in a theoretical profile along with the histogram of the actual densities. The background exponential profile was set to provide the correct density level in the theoretical profile. Using the layered medium model, the theoretical brightness temperatures for a range of ob-

4

'" a ~ 0.4 '"

o. 2

Through the creation of online biomedical databases, medical science continues to address the challenges of well-known diseases, such as Alzheimer s and relatively new diseases such as HIV and SARS These re sources enable collaboration among clinicians and scientists and provide the basis for decision support tools, gene chips, new therapeutic methods and other diagnostic devices On the scienti c horizon of medicine is a better understanding of the biological relevance of the human genome and proteome, especially how the less than 30,000 genes can de ne the human species Medical diagnosis a process based on the recognition of patterns of signs, symptoms, and laboratory results, is challenged to collect enough quality data for a human or machine to recognize different disease presen tations.

L------,5~0---:1-:-0:-0----,1~5":'O--2:-:0~O:---':'!.250

Depth (em)

Figure 1.2.2 Two sample realizations of a discrete random profile. The profiles are generated with an exponential distribution of layer thickness and a mean thickness of 4.1 em. The density in each layer is the sum of a deterministic part given by 0.25 (gjcm 3 ) + 0.16(1 3 exp(zj(20 cm)))(gjcm ) and a normally distributed random variable with zero mean and a standard deviation of 0.04 gjcm 3 (z is 0 at the top and negative in the medium). For display purposes, the resulting profile is then averaged over 5-cm intervals just as Rott's measured profile was (see Fig. 1.1.2). Calculation of brightness temperatures uses the original profile without the 5-cm averaging.

2 Ensure that there is a menu option and/or toolbar option on the MDI parent form that the user can use to display the child form 3 Add code in the Click event for the menu or toolbar option to create a form instance and set the MDI parent of the form to the instance of the MDI parent form

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